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L-Carnitine has been used for decades to support metabolic function

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[DOI] [PubMed] [Google Scholar] 104.Liu Y, Rosenthal RE, Starke-Reed P, Fiskum G

The rate of L-carnitine biosynthesis in humans was studied in strict vegetarians (i.e., in people who consume very little dietary carnitine) and estimated to be 1.2 mol/kg of body weight/day (9)

The tests were conducted on day 29, following the four-week treatment period

However, supplementing L-carnitine helps in the hemodialysis (HD) of dialysis patients via obviating comorbidities such as decreased exercise capacity, muscle symptoms, and increased intradialytic hypotension, as well as cardiac complications (arrhythmias, reduced output, low cardiothoracic ratio)