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Tractography imaging techniques to identify similarities in electrode contacts within deep brain stimulation responders have also highlighted the importance of four white matter bundles underlying area 25 [115]

New England Journal of Medicine , 379 (22), 21402150

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Dysregulated lipid metabolism in RA is characterized by elevated low-density lipoprotein Cholesterol (LDL-C), impaired high-density lipoprotein cholesterol (HDL-C) function, and abnormal proprotein convertase subtilisin/kexin Type 9 (PCSK9) accumulation, which directly drive inflammation and immune dysregulation