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R., Brayer, G

(2024) reported that in TP53-mutant AML cells, cytarabine and idarubicin combination increase the levels of the p53 and p21 proteins, and upregulated the G2/M-phase cell-cycle checkpoints regulators cdc25c, p-CDK1, and Cyclin b in DTP cells, causing cell cycle arrest in G2/M phase and drug-resistance

PubMed, Venn, Bernard J., et al

The active sites of GPx7 and GPx8 consist of a catalytic tetrad including Cys, Trp, Asn, and Gln/Ser residues

Introduction Oxidative stress (OS) is involved in the pathogenesis of cardiovascular diseases, such as hypertension, heart failure, atherosclerosis and ischaemia/reperfusion injury (IRI) [1,2,3,4,5,6]
