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Intravenous ferric carboxymaltose in iron-deficient chronic heart failure patients with and without anaemia: A subanalysis of the FAIR-HF trial

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Additionally, the expression of glucose regulated protein 78 (GRP78) and CHOP, both key hallmarks of ERs, is dramatically enhanced, and the IRE1/TRAF2/JNK signaling pathway is activated, which in turn increased the expression of Bax and inhibited the expression of Bcl-2, leading to hepatocyte apoptosis [8, 25]

[DOI] [PubMed] [Google Scholar] 28.Liu Y., Guerrero-Juarez C.F., Xiao F., Shettigar N.U., Ramos R., Kuan C.-H., Lin Y.-C., de Jesus Martinez Lomeli L., Park J.M., Oh J.W., et al