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Gene profiling showed that KLF4 was overexpressed in hAD-MSCs and hBM-MSCs compared with control fibroblasts

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In melanocytes 4-HNE, through adduct formation, alters protein function, contributing to oxidative stress-induced cellular dysfunction, which mainly concerns on the functioning of cellular antioxidant system, acceleration of protein degradation, inhibition of melanocyte proliferation, photoaging processes, but also disruption of the intercellular interactions between melanocytes and keratinocytes 101103

If they continue to be a problem for you, speak with your doctor about treatment options.

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Allergic Reactions: As with any supplement, a small percentage of people may experience a rash or itching