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Besides direct encapsulation of insulin, the hydrogel can also be used as part of the drug delivery system, together with particles loaded with insulin, as seen in the insulin-loaded sodium dodecyl sulfate and -cyclodextrin (SDS/-CD) vesicles-chitosan hydrogel

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Based on the Normo-Exos group data (which showed moderate improvement over untreated controls), we infer that the scaffold likely contributes to baseline structural support and partial ROS scavenging, while the EVs provide additional anti-inflammatory and neuroprotective benefits

A systems-based review

doi: 10.3390/GENES15050539 20

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