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94,95 All of the studies had small sample sizes, and study details are mostly not well reported

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In contrast, 10 studies investigated the relationship between B12 supplementation status and homocysteine levels, encompassing a total of 191 participants (mean: 19.1 per study)

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To get a clearer picture of your true B12 status (meaning whether B12 is getting to its needed places and if you have enough of it), testing B12 levels in the spinal fluid would be most accurate

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doi: 10.1016/j.fertnstert.2008.02.157

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contributed to study conception and design

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