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11 In the past, decompression surgery was an option to relieve stress on the facial nerve, but the benefits currently do not outweigh the risks, and permanent postoperative hearing loss has been reported in up to 15% of patients undergoing this procedure

Experimental models demonstrate that FOXO proteins mediate the inhibitory effects of insulin/IGF on target genes and are essential for maintaining metabolic homeostasis

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Side effects are typically mild and temporary, such as slight soreness at the injection site