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Source: Ma, L., and Y

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Comparable efficacy in clinical trials, minimal side effects, and lower monthly costs suggest that ALA and ALC should be considered among the accepted first-line treatment options for neuropathic pain

Instead, sleep quality, measured by PSQI score, has not shown any significant modification

436 Preclinical 69,434 and human genetic studies 69,437,438 in PDPN have shown evidence of enhanced function of voltage-gated sodium channels