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Safety Pharmacology studies assess potential effects of a new drug on physiological functions across a dose range that encompasses and surpasses therapeutic levels

[PubMed] [Google Scholar] 11.Sachan DS, Hongu N, Johnsen M

Inhibitors targeting purine or pyrimidine synthesis have also been utilized in hematological malignancies

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Emodin alleviates hepatic steatosis by inhibiting sterol regulatory element binding protein 1 activity by way of the calcium/calmodulin-dependent kinase kinase-AMP-activated protein kinase-mechanistic target of rapamycin-p70 ribosomal S6 kinase signaling pathway

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