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Apigenin also lowered VEGF expression in melanoma cells, suggesting anti-metastatic effects [104]

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Therefore, we summarize recent studies on the prevention and treatment of chemoradiotherapy-related cardiotoxicity by TCM and explain its mechanism to provide a basis for the prevention and treatment of chemoradiotherapy-related cardiotoxicity by TCM

While adequate folate intake appears protective before malignant change occurs, excessive folic acid exposure, particularly in susceptible individuals with reduced DHFR activity, may not always be desirable

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These criteria are unchanged and will remain unchanged regardless of the July 2026 PCAC outcome