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This, in turn, forms a vicious cycle that ultimately drives the development of MODS (74)

In addition to changes in mitochondrial dynamics, mitochondrial biogenesis is also induced after T cell activation and leads to increased mitochondrial mass, which is mediated by PGC1

Another major factor in cognitive decline and mood disorders is oxidative stress, which is markedly attenuated through the synergistic action of exercise and polyphenols

Evidence suggests that inter- and intra-neuronal mitochondrial diversity may explain the susceptibility of certain neuronal populations to specific mitochondrial disorders

Consequently, regular monitoring of thyroid function is recommended in individuals following KD, particularly those with conditions such as Hashimotos thyroiditis [12]

Redox-directed cancer therapeutics: Molecular mechanisms and opportunities
