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K.SteensbergA.FischerC.KellerC.KellerP.Plomgaardet al (2004)

The preservation of normal glucose-insulin dynamics with AOD-9604 is important for appetite neutrality, as blood sugar fluctuations and insulin spikes are major drivers of hunger and cravings

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An interesting example of such a model published by Roy et al., [170] consists of kinetic models of 53 metabolic reactions within glycolysis, glutaminolysis, tricarboxylic acid cycle and the pentose phosphate pathway represented as a set of ordinary differential equations fit to publish enzyme knockdown experimental data for pancreatic cancer