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Since this characteristic strongly correlates with tumorigenicity in animals [25], we hypothesized that interventions inhibiting TIC growth in 3D gels could also impede tumor development in vivo

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doi: 10.1111/j.1600-0773.1991.tb01264.x

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Migration inhibitory factor (MIF) Macrophage migration inhibitory factor (MIF) is a multipotent pro-inflammatory cytokine found in activated T lymphocytes and macrophages/monocytes, initially reported to be mainly involved in the innate and adaptive immune responses

These findings suggest that glutathione can be a practical addition to acne treatment regimens