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Genes Dev (1994) 8(9):101929

CB-839 treatment increased mitochondrial SOX in both cell lines at relatively low concentrations, starting at 10 nM for the HG-3 cell line and 100 nM for the MEC-1 cell line

However, clinical use has been challenging due to poor bioavailability and ineffective delivery [95]

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Weight, BMI, and hip and waist circumference decreased significantly in all groups, while only the 40:1 ratio group experienced a significant return of menstrual regularity

doi: 10.3389/fonc.2018.00549
