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Ang-2 disrupts vessel stability, promoting neovascularization, whereas Ang-4 enhances tumor angiogenesis

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Buchtk R, Trvnek Z, Vano J et al (2011) Synthesis, characterization, DNA interaction and cleavage, and in vitro cytotoxicity of copper(ii) mixed-ligand complexes with 2-phenyl-3-hydroxy-4(1H)-quinolinone