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Materials and methods Our study is based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) and the systematic review is reported according to PRISMA guidelines (Moher et al
Isoquercitrin also promotes immunogenic cell death (ICD) in human gastric cancer cells through ER stress activation ( Sustained ER stress upregulates the C/EBP homologous protein (CHOP), a predominant pro-apoptotic transcription factor in ER, triggering downstream cascade responses (Su et al., 2013)

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