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Supportingenergy production and overall cellular health

Reduced enzyme dynamics upon multipoint covalent immobilization leads to stability-activity trade-off

Shields and Shields 2015

Unlike PDE5 inhibitors that require sexual stimulation to work, MT-2 activates melanocortin MC4R receptors in the hypothalamus, producing centrally-mediated erections independent of arousal state

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Data availability The authors declare that all data supporting the findings of this study are available within the article and its Supplementary Information files