glutathione complex with arsenic trioxide trioxide: applications, mechanisms of action, toxicity and rescue strategies to date | Archives of Pharmacal Research Liquiritigenin protects against arsenic trioxide-induced

Additionally, when pristine Raw264.7 cells were treated with varying concentrations (0, 3, 6, 12, 25, 50, 75, 100, and 150 g/mL) of PDA and PDA@Pt, the PDA alone did not exhibit a significant decline in cell viability, while the PDA@Pt group showed a minor reduction at high concentrations, suggesting that the nanodrug is virtually non-toxic to normal Raw264.7 cells (Fig

Glutathione is a tripeptide (glutamate cysteine glycine) found in many cells that plays an important role in maintaining redox balance and reducing oxidative stress (Grant, 2001)

[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Ohta T, Iijima K, Miyamoto M, et al

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The Biochemical Journal, 406 (3), 407414