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(1951) [On the toxicity of selenium chloride.] Gig

Roles of dimerization domain residues in binding and catalysis by aminoacylase-1
The most frequent clinical presentation is the milder myopathic Type III form, which manifests with fluctuating proximal and axial myopathy with exercise intolerance and occasionally respiratory insufficiency [138] or rhabdomyolysis, although often with hepatomegaly, encephalopathy, and episodic lethargy, as well as vomiting and hypoglycemia often triggered by metabolic stress, episodes of which have been lethal in 5% of patients [140]

Therefore, enhancing peptide delivery systems becomes crucial in overcoming constraints associated with conventional injectable dosage forms, which involve repetitive dosing, lack long-term effects, and induce severe side effects

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