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Proc Natl Acad Sci USA 101: 31963201 Homem CC, Steinmann V, Burkard TR, Jais A, Esterbauer H, Knoblich JA (2014) Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells

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Those who are more active or have a naturally faster metabolism, are likely to see greater results than those who suffer from other medical conditions