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Indeed, preclinical studies conducted in renal carcinoma model reported that the VEGFR2 inhibitor sunitinib increases vascular mimicry under hypoxia by transforming tumor cells into endothelial-like cells resulting in tumor resistance [301]
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Immunol 12:295303 [DOI] [PMC free article] [PubMed] [Google Scholar] 97.Delgoffe GM, Kole TP, Zheng Y, Zarek PE, Matthews KL, et al
Asia Pac J Ophthalmol (Phila) 2013;2:132-5.ArticlePubMed 97
219 Low B 2 status has also been correlated with higher risk of cognitive dysfunction in older adults
