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R152 and active site residues C46, K48, Q81, and W136 are highlighted and shown as sticks

Spadaro, D

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Recently, Kim et al confirmed the effect of insulin on GSH levels and GCLC expression in rat hepatocytes and found that of the signaling pathways activated by insulin, PI3K/Akt/p70S6K are involved in mediating the effect while ERK, JNK and p38 MAPK are not (Kim et al., 2004)

The levels of ferric iron in the peripheral serum of patients with acute primary angle closure glaucoma are significantly higher than the average population, indicating that iron homeostasis is involved in regulating the damage of RGCs under pH IOP (Yao et al., 2023)

Am J Physiol - Cell Physiol (1997) 273:C137885