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The regulatory effect of GPX8 on Ca 2+ may be related to the inositol 1,4,5-triphosphate receptor (IP3R) effect, and the transmembrane domain (TMD) of GPX8 is thought to play a key role in the regulation of Ca 2+ signaling (Yoboue et al., 2017)

Trends Biochem Sci (2019) 44(5):46777

Studies have shown that adequate glutathione levels correlate with improved immune response and faster recovery from respiratory challenges

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