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Description
Fragment-based screening identifies molecules targeting the substrate-binding Ankyrin repeat domains of tankyrase

Dev Neuropsychol

The upper lobe is mostly -helical and contains the zinc binding site as well as the catalytically important residues

About 90% of the tryptophan is metabolized in this way

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Didangelos T, Karlafti E, Kotzakioulafi E, Kontoninas Z, Margaritidis C, Giannoulaki P, Kantartzis K