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Mitochondrial bioenergetics, redox state, dynamics and turnover alterations in renal mass reduction models of chronic kidney diseases and their possible implications in the progression of this illness

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In this study, groups with higher GGT levels showed dose-dependent elevations in all-cause mortality and cardiovascular disease when adjusted for age, sex, body mass index (BMI), blood pressure, alcohol consumption, and smoking

Itaconate, derived from citrate produced in the TCA cycle, contains ,-unsaturated carboxylic acid, and covalently modifies at the Cys151 residue of Keap1 (78)

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