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Sex differences in rotenone sensitivity reflect the male-to-female ratio in human Parkinsons disease incidence

doi:10.1016/j.bbr.2006.04.024 pmid:16750274 Urban JD, Mailman RB (2005) Characterization of the N27 dopaminergic cell line as a potential model for elucidating the mechanisms of action of functionally selective dopamienrgic ligands

Cardiotoxicity Two small RCTs: Conflicting results, one showed no effect, one showed reduced cardiac events

In females, CT2 is highly expressed in the endometrium

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