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Conversely, BSO treatment had little or no effect on cell survival, suggesting that GSH depletion does not play a key role in cell death caused by Cys deprivation (Fig

Insulin-like growth factor-I and -II levels are associated with the progression of nonalcoholic fatty liver disease in obese children

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Curcumin protects against myocardial infarction-induced cardiac fibrosis via SIRT1 activation in vivo and in vitro

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The first step is the combination of amino acids glutamate and cysteine by -glutamyl cysteine synthetase, also known as glutamate-cysteine ligase (GCL), to form gamma-glutamate-cysteine (-Glu-Cys) (Bottino et al., 2021, Lu, 2013, Wu et al., 2004)