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The physiological risks of testosterone therapy stem from its systemic actions

Therefore, the support for its therapeutic uses is limited, albeit largely optimistic

Highly expressed and mainly localized in endosomes and lysosomes of DCs, SLC15A3 is responsible for the transport of histidine and oligopeptides to cytosol (136)

But repeated injections carry real risks: plantar fascia rupture, fat pad atrophy, weakened tendon structure

The nephroprotective effect of the PROTAC has been confirmed in major nephrectomy and UUO models[86]

Cigarette smoke, whether through active or passive exposure, induces apoptosis, oxidative stress, and inflammation, ultimately accelerating cellular senescence and increasing the risk of premature mortality [183, 184]