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After 1 month of treatment in pernicious anemia patients, the once weekly dosing of 500 mcg B12 intranasal gel resulted in a statistically significant increase in B12 levels when compared to a once monthly 100 mcg IM dose

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doi: 10.1002/aur.2413

Romeos doctor did a full physical exampalpating his abdomenfinding some thickening of his intestines

2022/ABM/03/00013

Additionally, DSIP attenuates ACTH and corticosterone release in response to stress, indicating an effect on the hypothalamic-pituitary-adrenal axis [8]
