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Venoms as a platform for human drugs: translating toxins into therapeutics

Many animal studies have revealed the beneficial effect of BPC 157 therapy on muscle, tendon, ligament, and bone healing [80,81,82,83,84,85,86,87,88,89,90,91]

Subsequent phase I clinical trials demonstrated a strong synergistic effect of lenvatinib in combination with the EGFR inhibitor gefitinib in advanced HCC with high expression of EGFR and refractory to lenvatinib mono-therapy, with 9 out of 30 cases achieving partial response (NCT04642547)

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1 The discovery of vascular receptors that control vessel tone and neurohumoral mediators in hypertension has led to the development of modern antihypertensive drugs such as beta-blockers, angiotensin converting enzyme inhibitors, AT-1 receptor blockers or calcium channel blockers