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GSR is constitutively present in most cells, but can be induced in an Nrf2-dependent manner under oxidative stress, and it plays a crucial role in preserving the cellular redox state via the regeneration of GSH [62]

7 CHAC1 in cancer treatment CHAC1 has gained recognition as a critical factor in the evolving field of cancer treatment, presenting new opportunities to enhance therapeutic outcomes

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One of the causes of lens protein modifications is oxidative stress

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In summary, while prolonged UV-A exposure to mice in vivo induces a variety of cataract morphologies that differ to those observed in humans, these studies showed that elevated protein insolubility and impaired enzyme function are caused by UV-B irradiation