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However, NAD+ levels naturally decrease with age, potentially activating genes that hasten the aging process

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The main takeaway is that alcohol and research-grade peptides like CJC 1295/Ipamorelin have opposing physiological effects

Stress boosts cortisol and can interfere with ovulation and sperm production

The result is a vicious cycle where declining NAD+ leads to worse metabolic function, which can lead to weight gain, which increases NNMT activity further