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When the carotid artery and cerebral cortex of subjects within the control group were inspected, a high level of autophagy markers, light chain 3 (LC-3) and Beclin-1 (BECN-1), and apoptosis was found within the carotids as well as endothelial, vascular and cerebral cortex evidenced by a significant rise in caspase-3 expression and reduced Bcl-2 mRNA gene expression
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