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Common symptoms include: Fatigue and weakness One of the earliest and most common complaints Pale or yellowish skin Due to reduced red blood cell production Shortness of breath From anemia reducing oxygen-carrying capacity Numbness or tingling in hands and feet A sign of nerve damage Balance problems and difficulty walking Neurological manifestation of deficiency Memory problems or brain fog Cognitive effects of low B12 Mood changes, depression, or irritability Sore, red, or swollen tongue (glossitis) Mouth ulcers Constipation or diarrhea Neurological symptoms numbness, balance issues, cognitive changes can become permanent if deficiency is not treated promptly

Lancet Oncol 22:801812 Study of carfilzomib, daratumumab and dexamethasone for patients with relapsed and/or refractory multiple myeloma (CANDOR)

Incorporate vitamin B12-rich foods into your diet to ensure you meet the recommended daily intake

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We recently received a query from a reader concerned about depression and memory deficits associated with one of these drugs

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