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Metal export by CusCFBA, the periplasmic Cu(I)/Ag(I) transport system of Escherichia coli

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This timing has two advantages: it aligns with your body's natural growth hormone peak during slow-wave sleep, and it ensures insulin levels are low enough to avoid blunting the GH pulse

doi: 10.1016/j.jdermsci.2023.04.006

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