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The authors reflect on recent imaging and fluid biomarkers for Parkinsons and consider challenges in bringing them into clinical use.

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Trimethylglycine (TMG) assists homocysteine to be metabolized into methionine, resulting in the production of DMG (dimethylglycine).* Further metabolism of TMG produces the enzyme methyltetrahydrofolate reductase (the active form of folic acid)

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