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Younger mice exposed to a prolonged high-fat diet and hyperglycemia showed increased insulin, glucose, and frequency of activated microglia in the dentate gyrus of the hippocampal formation and cornu ammonis of the hippocampus (Yao et al., 2023)

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Delgado M, Ganea D

Curcumin shows neuroprotective effects by stabilizing mitochondrial membrane potential, inhibiting cytochrome c release and subsequent caspase-3 activation, leading to reduced apoptosis (Jayaraj et al., 2013)