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Extended data figures and tables Extended Data Fig

Although the authors generated multiple tissue-specific Slc25a45 KO models and concluded that systemic carnitine availability reflects coordinated contributions from multiple organs, fuel reliance is likely to vary with dietary regimen, metabolic state, and pathology

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In advanced cases of PDR, the financial burden is further compounded by surgical interventions such as vitrectomy, which carry not only higher costs but also increased risks and variable outcomes depending on systemic comorbidities and the severity of retinal damage