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The molecular mechanism regulating PO-induced melanin synthesis was studied in T
In neuroendocrine prostate tumors, loss of tumor suppressor protein kinase C (PKC) / enhanced serine metabolism through mTORC1/ATF4/PHGDH axis, which leads to aberrant DNA methylation by increased one-carbon metabolic flux, ultimately leading to treatment resistance and poor prognosis [98]
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If successful, setmelanotide can be used in an expanded population of people with obesity and with other rare genetic diseases
Effect of selected environmental and physico-chemical factors on bacterial cytoplasmic membranes
