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Superdex 200 10/300 GL column connected with KTA Avant system (Cytiva, Marlborough, MA, USA) was used

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J Pathol 210 : 249257

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Nature 431, 811818

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Research published in Clinical Immunology explored this further

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Cytochrome b5 reductase (CBR) deficiency is an enzymopathy that does not cause hemolytic anemia: it instead causes recessive congenital methemoglobinemia, 29 often presenting as cyanosis in infants, that may mislead one to suspect congenital heart disease

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