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[13] Physiological vitamin D sufficiency is vital for placental function, foetal bone accretion, and maternal skeletal health, yet professional bodies caution against parenteral megadose therapy during uncomplicated gestation, preferring daily or weekly oral regimens that allow tighter titration and minimise abrupt calcium flux

[20] This effect was confirmed in a 2017 meta-analysis

Carr, A

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Preclinical studies and clinical trials evaluating CD38 inhibition are ongoing in patients with either solid tumors or hematological malignancies, including MM ( 2.4 CD38 enzyme activity and therapeutic antibodies: potential influence on refractoriness A crucial question is whether the binding of therapeutic CD38 antibodies interferes with the enzymes functional activity