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Description
Beyond inflammation-specific triggers, CS can be driven by broadly acting homeostatic disturbances, including macromolecular injury, glucotoxicity/lipotoxicity, chronic hypoxia, energetic stress (an increased AMP/ADP/ATP ratio), redox imbalance, and electrolyte shifts that threaten cellular viability

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J Biol Chem 275(24):1812118128 Zhong L, Persson K, Sandalova T, Schneider G, Holmgren A (2000b) Purification, crystallization and preliminary crystallographic data for rat cytosolic selenocysteine 498 to cysteine mutant thioredoxin reductase

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Excellent cooperation, all recommendations

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