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Ficlatuzumab (AV-299) is a humanized monoclonal anti-HGF IgG1 antibody that enchains to HGF, thereby inhibiting the HGF/c-Met interplay

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In clinical trials, 12.3% of patients (10/81) with diabetes developed urinary retention following treatment with BOTOX 100 Units vs 0% of patients (0/69) treated with placebo

Eleven lncRNAs and four mRNAs including pro-apoptotic gene Hif3a were significantly differently expressed after DMDD treatment in the hippocampi of db/db mice