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doi: 10.1073/pnas.1203519109, 53 VoroninD.TricocheN.PegueroR.KaminskaA

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Despite this significant effect, doxycycline is unsuitable for implementation in mass drug administration (MDA) programs due to the logistics of delivering a relatively long course of treatment and its contraindication in pregnancy, during breastfeeding and in children below the age of 8 years old (Taylor et al., 2013a)