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doi: 10.4103/cjp.cjp_95_20

Remarkably, one double-blind randomised trial found that both 20 g/mL and 40 g/mL doses effectively reduced pain without significant differences between concentrations, suggesting a threshold effect where lower doses sufficiently activate therapeutic pathways

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While preclinical results show promising directions, the exact mechanisms, tissue-specific actions, and translational relevance remain incompletely defined

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