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Conflicts of Interest The authors declare no conflict of interest References 1.Holshue M., DeBolt C., Lindquist S., Lofy K., Wiesman J., Bruce H., Spitters C., Ericson K., Wilkerson S., Tural A., et al

Understanding mast cells as neuroimmune amplifiers helps explain why many autoimmune brain disorders present with fluctuating, multisystem symptoms neurological, psychiatric, gastrointestinal, and dermatological and why traditional autoimmunity testing often misses key contributors

47 , S29

While B12 plays a role in cellular energy metabolism, supplementing B12 in a patient who is not deficient does not increase metabolic rate or cause fat loss

C.Agreda-MellonD.LucioJ.Mendes-GianniniM

Similarly, ATM impacts cell death by regulating apoptosis, autophagy, and possibly necroptosis (Liang et al., 2013
