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APOL1 risk variants, incident proteinuria, and subsequent eGFR decline in blacks with hypertension-attributed CKD
FIGURE 2 2.1 Forming the basis: antioxidant and metabolic enhancement The most studied antioxidant supplement in stored RBCs is ascorbic acid, with human studies indicating that it attenuates oxidative stress and lesions (Tzounakas et al., 2022a) and boosts antioxidant defenses (Ravikumar and Rajashekaraiah, 2017)
In addition, many drugs and toxins have oxidant activity and appear to generate superoxide
10.1074/jbc.m303302200 255 YangX.HeC.LiJ.ChenH.MaQ.SuiX.et al
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doi: 10.1007/s40257-022-00744-6 32
