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The aspartate which is also produced is translocated out of the mitochondrion, in exchange for glutamate, through the actions of the SLC25A13 antiporter
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Inhibiting the release and uptake of KRASG12D can suppress macrophage-mediated tumor growth in pancreatic cancer [109]
Cell-based and ecm-targeted therapies Mesenchymal Stem Cells (MSCs) provide both regenerative and immunomodulatory functions
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