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Patients should never initiate this combination without explicit physician guidance, as both medications require prescription authorization and medical supervision

Li Y, Li W, Liu Y, Liu J, Yuan X, Zhang J, Shen H

Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial

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Reductions in alcohol craving following naltrexone treatment for heavy drinking

Adhering to recommended dosages is key to safe use
